{"id":124182,"date":"2026-05-07T11:36:01","date_gmt":"2026-05-07T11:36:01","guid":{"rendered":"https:\/\/christiancorner.us\/index.php\/2026\/05\/07\/10-things-you-might-not-know-about-the-use-of-glp-1s-in-perimenopause\/"},"modified":"2026-05-07T11:37:27","modified_gmt":"2026-05-07T11:37:27","slug":"10-things-you-might-not-know-about-the-use-of-glp-1s-in-perimenopause","status":"publish","type":"post","link":"https:\/\/christiancorner.us\/index.php\/2026\/05\/07\/10-things-you-might-not-know-about-the-use-of-glp-1s-in-perimenopause\/","title":{"rendered":"10 things you might not know about the use of GLP-1s in perimenopause"},"content":{"rendered":"<p>\n<\/p>\n<div end=\"true\">\n<p>This is probably the most underappreciated piece of the puzzle. Research has shown that estrogen actually increases GLP-1 production in both the intestine and pancreas. Estrogen stimulates GLP-1 release by activating specific receptors. As estrogen decreases during perimenopause, GLP-1 signaling also weakens, leading to increased appetite, fat accumulation \u2014 especially around the belly \u2014 and difficulty managing blood sugar, even if your habits haven&#8217;t changed. Microdosing GLP-1 can, to some extent, be thought of as replacing a signaling pathway that your body is missing.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>This is probably the most underappreciated piece of the puzzle. Research has shown that estrogen actually increases GLP-1 production in both the intestine and pancreas. Estrogen stimulates GLP-1 release by activating specific receptors. As estrogen decreases during perimenopause, GLP-1 signaling also weakens, leading to increased appetite, fat accumulation \u2014 especially around the belly \u2014 and<\/p>\n","protected":false},"author":1,"featured_media":124183,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[60],"tags":[17350,7694],"class_list":{"0":"post-124182","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-meditation","8":"tag-glp1s","9":"tag-perimenopause"},"_links":{"self":[{"href":"https:\/\/christiancorner.us\/index.php\/wp-json\/wp\/v2\/posts\/124182","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/christiancorner.us\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/christiancorner.us\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/christiancorner.us\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/christiancorner.us\/index.php\/wp-json\/wp\/v2\/comments?post=124182"}],"version-history":[{"count":1,"href":"https:\/\/christiancorner.us\/index.php\/wp-json\/wp\/v2\/posts\/124182\/revisions"}],"predecessor-version":[{"id":124184,"href":"https:\/\/christiancorner.us\/index.php\/wp-json\/wp\/v2\/posts\/124182\/revisions\/124184"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/christiancorner.us\/index.php\/wp-json\/wp\/v2\/media\/124183"}],"wp:attachment":[{"href":"https:\/\/christiancorner.us\/index.php\/wp-json\/wp\/v2\/media?parent=124182"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/christiancorner.us\/index.php\/wp-json\/wp\/v2\/categories?post=124182"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/christiancorner.us\/index.php\/wp-json\/wp\/v2\/tags?post=124182"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}